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IGF-1 LR3 has a 13-amino acid N-terminal extension plus an arginine substitution at position 3, totaling 83 amino acids

Endocrine 50 , 620626 (2015)

He reviewed pre-clinical data, including findings from his own research group, and discussed how these results support GLP-1 agonists as a potential new therapeutic class for OA

[12] The oral upper intake levels established for dietary copper do not translate directly to a copper-carrying peptide delivered subcutaneously, which bypasses the intestinal regulation of copper absorption entirely one more reason the systemic dosing of GHK-Cu is genuinely uncharacterized in humans

GLP-1 enhances renal function by vasodilating the kidney vessels, increasing blood flow and lowering angiotensin II, which are important for controlling vascular tone