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[46] NAD+ levels drop as we age, and low NAD+ levels are correlated with many diseases [47-49] -- these disease may even be caused by low NAD+ levels

doi: 10.1016/j.ajhg.2018.12.001

Shin SY, Kang SW, Lee DG, Eom SH, Song WK, Kim JI: CRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity

Within this concept FOXO factors antagonize classical growth factor signaling promoting repair processes

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