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Leg cramps are not one of the most common side effects of semaglutide, which include nausea, vomiting, and diarrhea

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Hepatic lipid accumulation in healthy subjects: a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy

That generous space matters because proper GLP-1 injection technique requires rotating within the same general region, and the thigh gives you plenty of room to move around without reusing the same spot twice

The label only mentions that Wegovy is not recommended in patients with severe gastroparesis. Gastroparesis should be treated seriously