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It's crucial to share your full medical history, including any allergies (especially to cobalt) or existing conditions like kidney disease

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Causes: Vitamin B12 deficiency, nerve compression (sciatica, herniated disc), multiple sclerosis, peripheral neuropathy

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Prajapati SK, Wang S, Mishra SP, Jain S, Yadav H

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Spironolactone is commonly used in this setting because it targets androgen-driven changes rather than directly targeting estrogen levels

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Additionally, the membrane expression of TfR1 is positively regulated by PKC phosphorylation, which in turn promotes iron uptake

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doi: 10.1016/j.cbi.2019.108891 127 MohandasS.VairappanB

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