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Zhu D, Li X, Ma J, Zeng J et al (2022) Dorzagliatin in drug-nave patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial

Replacing a vial early when you suspect potency loss costs less than continuing ineffective injections for weeks

Retatrutide dosing comes from the Phase 3 TRIUMPH program titration

In fact, the UK government recommends that women on GLP-1s use condoms alongside the pill at least while starting or increasing doses or switch to non-oral contraceptives, such as the coil or implant

None of them had diabetes

Current data suggests that the relevance of targeting MC1R mediated pathways may depend on receptor expression levels and genetic background, emphasizing the need for continued research to clarify the receptors protective roles within epidermal layer biology