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Nonetheless, different animal models deficient for GLP-1 signaling, in addition to human studies, prove the dispensability of GLP-1 for surgical success ( On the other hand, PYY has been proven to be upregulated, and necessary, for RYGB mediated restoration of the diabetic islets, and overall cure of diabetes in rats (154)

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Conversely, E treatment alone failed to normalize estrous cyclicity in the PNA model, as 63% of E-treated PNA mice displayed clear signs of perturbed ovarian cyclicity (Fig

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