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Despite these positive results, case reports in both adults and children have reported neem oil poisoning incidents causing vomiting, seizures, hepatic toxicity, metabolic acidosis, and toxic encephalopathy (Sinniah and Baskaran, 1981
The mechanism of action may involve corilagin binding to HCV N53 protease, forming an enzyme-inhibitor complex that can alter or deactivate the enzymes activity structure (Yue et al., 2005)
4-PBA improves lithium-induced nephrogenic diabetes insipidus by attenuating ER stress
However, it is to be noted that the results in animal models may not be similar to the results in humans
Works as an anti-aging product by reducing the fine lines and hides the signs of aging