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Targeted biologic therapies under evaluation for SLE include anifrolumab, belimumab (intravenous and subcutaneous formulations were registered by FDA for use in SLE in 2017) and off-label rituximab, abatacept, tocilizumab, obintuzumab, and eculizumab.[3] The novel biologic therapy, telitacicept, is currently under investigation

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