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Avoid using this drug in patients with a personal or family history of MTC or patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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Kidney impairment Semaglutide is generally safe in patients with mild to moderate kidney impairment without needing dose adjustment

Additionally, the proportion of participants from ethnically diverse backgrounds was relatively small, as most of the RCTs included in this SRM were conducted in Europe and America