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Vitamin C only blocked this effect after a single dose, not sustained daily use

In addition, the chemokine CCL5, as a key effector molecule of T cells and NK cells, mediates interactions between immune cells, vascular endothelial cells, and smooth muscle cells by binding to receptors such as CCR3 and SDC4, exacerbating vascular occlusion (Li et al., 2024c)

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151,152 GDH1 depletion results in imbalanced redox homeostasis and cell cytotoxicity and attenuates cancer cell proliferation, which as well as the results in erythroleukemia cells, while it negligibly affects normal cell proliferation