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Even though lower doses are presumably safer, using them would still require a new pre-IND safety justification, dose-range toxicology studies, and possibly a new manufacturing lot release. That would add ~12 years of delay

It looks like refined sugar and has a very pleasant taste

Increased Fermentation When food moves through the gut more slowly, it spends more time in contact with intestinal bacteria

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TB-500's anti-inflammatory effects may reduce post-exercise soreness that sometimes limits therapy intensity