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The last line of defense consists of numerous immunocytes and immunoreactive substances

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doi: 10.3390/genes11101208 517 AfzalAHussainTHameedAShahzadMMazharMUYangG

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Prescribing outside the licensed indications and doses constitutes off-label use, which requires prescribers to document their rationale, obtain informed consent, and provide appropriate monitoring

In fact, these clinical guidelines reflect the growing recognition of obesity as a chronic condition that benefits from sustained treatment, as opposed to a problem that needs to be solved in a matter of weeks