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Many protocols combine both approaches

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Crossbreeding of UCHL-eGFP with prpTDP-43 A315T mouse model of ALS, generated prpTDP-43 A315T -UeGFP mice (diseased) and WT-UeGFP mice (healthy control)

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Several aspects of the current dosing framework may change based on ongoing research, and staying informed about these developments helps researchers plan future protocols

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