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If you are going to be treated with a drug known to cause tinnitus, your healthcare provider may order a baseline hearing test before starting treatment

Frequent users remained on the unit 72 h post-dose and left the unit for a minimum of 72 h between sessions

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One specific caution Sean raised is worth highlighting: TFA (trifluoroacetic acid) is the default ion-pairing agent for many laboratories, and it performs well for many separations