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Clinical trials show that about 85 to 90 percent of participants lose at least 5 percent of their body weight, which is considered clinically significant weight loss

Metabolic syndrome with elevated liver enzymes : Patients presenting with multiple metabolic risk factors (central obesity, hypertension, dyslipidemia, impaired fasting glucose) and persistently elevated ALT/AST may benefit from the comprehensive metabolic improvements offered by GLP-1 therapy

Before taking semaglutide, speak with your healthcare provider to understand the potential risks associated with this medication and whether or not it is right for you

If you are using a vial, you will also need your bacteriostatic water and appropriate syringe with needle (typically 27-30 gauge, 1/2 inch for most adults)

If your primary concern is fatigue and low energy , B12 makes more sense

Never double-dip a needle into the vial