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In mice, the loss of JNK1 and JNK2 led to more severe age-related OA and ageing of cartilage and synovium (Loeser et al., 2020), an indication that JNK is a detrimental regulator of joint degeneration
Biochemical Assays: Studying specific peptide-receptor interactions or enzymatic responses in isolated cell cultures
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Animal studies have shown a significant reduction in postoperative complications, particularly anastomotic dehiscence
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