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I also tell them animal studies are not human studies and do not correlate. The medical saga of thalidomide, which was tied to severe birth defects when taken during pregnancy in the late 1950s and early 1960s, initially appeared to be safe in animal studies

doi: 10.3389/fnbeh.2020.614884

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Due to its impact on mitochondrial function, a hallmark of APAP hepatotoxicity is the robust production of reactive oxygen species (ROS) 28

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