In contrast, those who only implemented lifestyle changes saw an average decrease of 2.4% in their weight
Abramov A, Schorr S, Wolman M
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Notably, one-third of participants lost at least 25% of their body weight, compared to a 17.5% reduction with the 2.4mg dose and just 2.4% with a placebo
The more recent Phase 3 TRIUMPH 4 trial showed even more impressive results, with participants losing up to 28.7% of their starting weight over 68 weeks
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