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Importantly, the authors described an intensive mineralized layer localized to the marginal bone exclusively around UV-treated implants, supporting the concept of bone seal with a stronger, more continuous, and more mature interfacial architecture rather than more bone alone [153]

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The therapeutic approach for HCC remains focused on curative treatments for early stages (resection, ablation, transplantation) or palliative systemic therapies for advanced disease (tyrosine kinase inhibitors [TKIs] and VEGF inhibitors) and immunotherapies (i.e., programmed death 1 [PD-1]/programmed cell death-ligand 1 [PD-L1] inhibitors and anti-cytotoxic T-lymphocyte-associated protein 4 [CTLA-4] antibodies) (Sadagopan et al., 2024

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doi: 10.4254/wjh.v1.i1.72 66 XuDXuMJeongSQianYWuHXiaQet al