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Today, there is no scientific evidence that this happens, but a related drug in the class, tirzepatide (Mounjaro, Zepbound), carries warnings on its FDA labels that it may reduce the efficacy of oral hormonal contraceptives due to delayed gastric emptying. Patients are advised to switch to a non-oral form of contraception or to add a barrier method, such as condoms

Here's how the dose escalation typically looks over several months: Remember, these are general guidelines

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It's worth noting that about 1 in 12 people in clinical trials experienced diarrhea regardless of their dose

If your acne occurs alongside other symptoms such as menstrual irregularity or excess facial/body hair, your GP may also consider assessment for hormonal conditions like polycystic ovary syndrome (PCOS)

The steady-state blood level that comes from consistent weekly dosing is what drives sustained appetite suppression and metabolic benefits