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Based on our findings, these alterations do not seem enough to shorten the time from MBS to the development of PBH, even though cholecystectomy induces hypoglycemic kinetic changes in BA

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Epac2 interaction with Rim2 and Piccolo is crucial for cAMP-induced Ca 2+ -dependent insulin secretion and is not blocked by inhibition of PKA [493,512,513]

Menopause Women going through menopause may be more likely to gain weight as a result of hormonal changes

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