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Adverse Effects In the phase 2 TROPION-Lung05 trial, treatment-related adverse effects (TRAEs) of grade 3 or higher were observed in 28.5% of patients, and the most common included stomatitis (9.5%), nausea (2.2%), and decreased appetite (2.2%)

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Factors related to age at depression onset: the role of SLC6A4 methylation, sex, exposure to stressful life events and personality in a sample of inpatients suffering from major depression