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Prooxidant activities of antioxidants and their impact on health

In patients with progressive myoclonus epilepsy, a GSTT1 -null genotype has been associated with increased risk of developing the disease where it might contribute to enhanced susceptibility to oxidative stress 60

The increased ROS level impacts the integrity of the RBC membrane, which impacts the red blood cell (RBC) function, leading to impaired hemostasis and thrombosis