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Weeks 5-8: For many users, this is when adaptation begins

These high costs can limit which patients have access to drugs needed to treat type 2 diabetes or manage obesity

Dr Channa Jayasena, a consultant in reproductive endocrinology and andrology at Imperial College healthcare NHS trust, said: GLP-1 drugs copy the natural hormones made in the gut which make you feel full

For users exploring whether they can lose weight on semaglutide without exercise , the answer is yes, but the quality of weight loss, specifically the ratio of fat to muscle lost, is significantly worse without resistance training

Average: 1 to 2 percent body weight loss (2 to 5 pounds for most starting weights)

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