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Tryptophan is first decarboxylated to tryptamine by tryptophan decarboxylase (TDC), then transform into 5-HT by tryptamine-5-hydroxylase (T5H), and finally convert to MT through two additional enzymatic steps 6,7,8

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3.2.1 Uptake and signaling of exogenous lipids Extracellular lipids, particularly fatty acids of varying chain lengths, exert selective effects on T cell fate