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In melasma, the mean reduction of the modified MASI (mMASI) by treatment with a broad-spectrum sunscreen and topical 4% HQ is expected to be 3040% after 8 weeks and 4555% after 16 weeks [30, 31]

Research increasingly shows that irisin plays a role in regulating lipid and glucose metabolism in skeletal muscle and adipose tissue (Xiong et al., 2015

Pharmacokinetics of exogenous melatonin in relation to formulation, and effects on sleep: A systematic review

Emerging evidence also highlights the importance of dietary modifications to mitigate these risks

AK activity depends on the presence of Mg 2