STAT3 upregulates the protein expression and transcriptional activity of beta-catenin in breast cancer
Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis
Therefore, further investigation of systemic and local mitophagy mechanisms is required to elucidate LN
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While the passive technique focuses on drug and vehicle interaction and optimization to affect the stratum corneum structure, the active approach utilizes external energy to facilitate the transportation of drugs through the skin or by physically disrupting the outermost layer of the skin, known as the stratum corneum [230, 231]
Reported side effects include skin rashes, abdominal pain (in rare instances), and temporary lightning in patches, which normalizes during treatment