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Healthcare providers may only recommend GLP-1 receptor agonists when BMI is over 30 (i.e., obesity), or if BMI is over 27 and the patient has an associated health condition, such as diabetes, kidney disease, or obstructive sleep apnea

A It study also found that weight loss from oral semaglutide in the study participants was dose-dependent

Pharmacology 74 , 919, (2008)

In fact, many patents covering GLP-1RAs are drug-device combination patents or formulations adapted for particular administration routes, such as oral or subcutaneous formulations