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In HFD-induced atherosclerotic mice, BBR treatment exerts a beneficial effect on reducing circulating lipid levels (Wu et al., 2020) by increasing the abundance of Akkermansia, Firmicutes, and Verrucomicrobia (Zhu et al., 2018) and decreasing the abundance of Bacteroidetes and Proteobacteria in the mouse intestinal flora (Shi et al., 2018)

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doi: 10.1093/gerona/glw126 [DOI] [PMC free article] [PubMed] [Google Scholar] 25

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Reduce by 0.25mg if this pattern appears across multiple administrations