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They consistently show that acarbose improves glucose tolerance, reduces gastrointestinal hormone release and reduces the incidence of hypoglycaemia, which is the main feature of late dumping syndrome 12,76,107,108,109,110,111,112,113,114,115,116

reported that IRI-induced AKI mice with gut dysbiosis exhibited reduced SCFA levels and impaired metabolic activity in the renal tubular epithelial cells, which collectively promoted CKD development and renal fibrosis [169]

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Moreover, the overexpression of COX-2 is often closely associated with chemotherapy resistance and immune escape processes in tumors, suggesting that COX-2 is an attractive therapeutic target in tumors (107)

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