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In an oxygen-rich environment, iron can react with different types of phospholipid hydroperoxides and lipid (fatty acid) hydroperoxides to generate reactive oxygen species (ROS) through the Fenton reaction

[1] [8] When used with insulin or sulfonylureas, there is an increased risk of hypoglycaemia, which may require dose adjustments of these medications

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By the time researchers in the 1970s linked low GSH levels to HIV progression, liver disease, and neurodegenerative conditions, decades of patients had progressed without intervention