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A sample can test high on purity and still diverge meaningfully from the label claim on quantity

The most frequent gastrointestinal side effects include: Nausea and vomiting : Very common, typically most pronounced during dose escalation Diarrhoea : Common to very common, though usually mild to moderate Constipation : Can occur due to delayed gastric emptying and reduced gut motility Abdominal pain and discomfort : Common Dyspepsia and gastro-oesophageal reflux : May worsen in susceptible individuals Other important adverse effects include: Gallbladder disorders : Cholelithiasis and cholecystitis have been reported, particularly with weight loss Dehydration and acute kidney injury : May occur secondary to severe gastrointestinal symptoms Hypoglycaemia : Risk increases when used with insulin or sulfonylureas, which may require dose adjustment Current limited evidence does not suggest an increased risk of inflammatory bowel disease (IBD) flares with GLP-1 agonists, though more data are needed

In fact, a recent study and release from the American Academy of Ophthalmology and the North American Neuro-Ophthalmology Society issued a statement that anyone who is taking a weight loss injectable with semaglutide and has a sharp or sudden loss of vision, should immediately stop taking the drug and get evaluated by a doctor

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Walter Bernacki