Patients reduced 3-5% of their body weight after using it for 6 months
Consistency is more important than perfection
The literature is conflicting on this topic, and although in vitro studies in obese mice have shown a positive effect of semaglutide in promoting muscle protein synthesis, increasing the relative proportion of skeletal muscle, and improving muscle function [119, 120], a synergistic dietary strategy such as the MD may help mitigate this concern and optimise the quality of weight loss
That still leaves a comfortable margin above the 48-hour or 72-hour minimums
Switching to Wegovy or Zepbound ensures a regulated, consistent, and effective approach to achieving and maintaining weight loss
This then led to the development of Saxenda (liraglutide) and Trulicity (dulaglutide), which were FDA-approved for obesity and diabetes , respectively, in 2014