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G6PD-deficient cells are unable to generate enough NADPH under the condition of severe thiol depletion and GSH biosynthesis and methionine cycle are upregulated at the expense of ATP but fail to compensate for GSH depletion (311)

The phase 3 ATTAIN-1 trial compared results for 3127 adult participants with obesity, or who were overweight with a weight-related medical problem, and who did not have diabetes

The specific dose varies depending on the individual's requirement and condition