Results were good
Fewer Digestive Side Effects Some people experience side effects from taking oral supplements, including: Upset stomach Nausea Constipation or diarrhea Bloating These side effects are often due to the fillers and binders used in pills or the digestive stress of breaking down high concentrations of nutrients
Improved circulation and reduced inflammation also suggest benefits for the gut-brain axi, possibly easing brain fog, mood swings, and cognitive fatigue that plague so many patients
Amylin/Calcitonin Receptor Agonism (cagrilintide) Delays gastric emptying, reduces postprandial glucagon, and strongly promotes satiety Modulates appetite-regulating centers in the hindbrain, hypothalamus, and brain reward circuits, directly influencing food intake and choice May transiently activate the renin-angiotensin-aldosterone system with dose escalation, but without blood pressure or electrolyte derangements GLP-1 Receptor Agonism (semaglutide) Stimulates glucose-dependent insulin secretion and suppresses glucagon release to improve glycemic control Reduces appetite and ad libitum energy intake, with central effects on GLP-1R-expressing nuclei in hypothalamus and brainstem Delays gastric emptying and increases satiety, contributing to progressive bodyweight loss Pharmacokinetic Profile Route of Administration Subcutaneous Dosing Frequency Once weekly Route of Administration : Subcutaneous Injection Dosing Frequency: Once weekly Half -life: Cagrilintide: 7-8 days
others use them occasionally for a boost.
150 MahecicD.CarliniL.KleeleT.ColomA.GoujonA.MatileS.et al (2021)
