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One nuance worth knowing: some patients on GLP-1 and dual GIP/GLP-1 medications see a temporary increase in LDL during rapid weight loss phases

Recent FDA approvals have expanded the indication for semaglutide to include the reduction of major adverse cardiovascular events (MACE), such as heart attack, stroke, and cardiovascular death, in adults with established cardiovascular disease and obesity

Customize your order: Dont be afraid to request modifications to your meal, such as asking for grilled instead of fried options or swapping a side of fries for a salad

Have ginger tea or ginger capsules ready if you are prone to nausea

Patients were randomly assigned to orforglipron (12 mg or 36 mg) or semaglutide (7 mg or 14 mg) with a treatment period of 52 weeks, from 22 September 2022 to 22 August 2025, and drugs were administered orally once per day