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Vitamin B6 (Pyridoxine) acts as a necessary cofactor in the folate cycle and combines with serine hydroxymethyl transferase to effect the conversion of tetrahydrofolate(THF) to 5,10 methylene THF (14)
An aminoisobutyric acid (Aib) substitution at position 8 resists degradation by the DPP-4 enzyme
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A Low blood levels of certain B vitamins, including B12, B6, and folate, have been linked to an increased risk of depression, which is why its important to rule out nutrient deficiencies if you are experiencing symptoms of depression
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