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Majzoub A, Agarwal A

Similarly, acetaminophen overdose leads to the formation of a toxic metabolite, N-acetyl-p-benzoquinone imine (NAPQI), which depletes glutathione and induces oxidative stress in the liver [57]

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6.6.4 Glucocorticoids The presence of glucocorticoid receptors in endothelial and inflammatory cells (240243), as well as increased concentrations of circulating glucocorticoids at the onset of inflammation downregulating inflammatory responses, is proof that glucocorticoids are modulators of inflammatory responses (243, 277)

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