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Retatrutide has shown approximately 24% body-weight reduction in phase 2 obesity research at the highest studied dose over 48 weeks [8], while REDEFINE 1 Phase 3 data reported 22.7% mean weight reduction with CagriSema at week 68 [3]

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In addition to having 2 to 4 times greater risk for stroke, diabetes is the leading cause of blindness in Americans 20-74 years of age (1)

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Relative mRNA expression levels of target genes were normalized to GAPDH and calculated using the 2 Ct method

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