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Based on the saturable metabolism of phenytoin, this may cause phenytoin levels to gradually drift upwards over time (discussed in the section above)

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Molecular dynamics studies Molecular Dynamics (MD) simulations were performed for the apo AlphaFold prepared structure of SLC25A45, as well as when in complex/docked to the ligand TML

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45,46 Increasingly, more studies have shown that G6PD activity is increased in several types of cancers, including bladder, breast, prostate, gastric cancers compared with normal tissues, and the high expression of G6PD predicts poor clinical outcome in various cancer patients and plays critical roles in tumorigenesis and chemoresistance