Several of these markers are hypothesized to be of relevance in CV disease (IL-1 receptor antagonist, IL-1 receptor, MMP3, CD163, IL-6 and its receptor) (242245)
Its also helpful for weight loss and protects the heart and kidneys from dangerous events
Some patients find that medication-induced weight loss lessens rather than improves fitness, because another side effect is muscle loss
This isnt necessarily a failure of either medication
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GLP-1, short for glucagon-like peptide-1, is a hormone released in the small intestine after eating