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In addition to demonstrating KL1s activity in THP-1-derived human macrophages and primary human neutrophils, we further examined whether macrophages derived from human peripheral blood mononuclear cells (PBMCs) could recapitulate the response

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All participants that completed the primary efficacy phase were asked to participate in a 26-week extension phase as well

Akt phosphorylation, which demonstrates PAM activation, occurs in 50% to 70% of NSCLCs and 30% to 66% of head and neck squamous cell carcinomas (HNSCCs) [81, 82]