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Metallothionein 1G (MT1G), which is related closely to GSH reductase, is upregulated in ccRCC cells and may inhibit ferroptosis by regulating GSH consumption (89)

Nevertheless, current knowledge of such strategies is far from complete, and well-designed studies are needed to define whether these interventions will also result in a concomitant reduction in the risk of incident cardiometabolic disorders

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Diabetes Res Clin Pract 115:3946 Karamali M, Heidarzadeh Z, Seifati SM, Samimi M, Tabassi Z, Hajijafari M, Asemi Z, Esmaillzadeh A (2015) Zinc supplementation and the effects on metabolic status in gestational diabetes: a randomized, double-blind, placebo-controlled trial

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doi: 10.1016/S0014-2999(98)00818-8