Data from animal studies further suggest that the appetite suppressant (anorectic) effects of GLP-1R agonists are also manifested through mesolimbic GLP-1R activation, that in turn alters the rewarding value of food [23,24,25,26,27,28,29]
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And in a remarkable mouse study published in Cell Metabolism in early 2026, researchers at the Chinese Academy of Sciences showed that semaglutide preserved cartilage and reduced joint inflammation in osteoarthritic mice even when pair-fed control mice lost the same amount of weight but showed continued cartilage deterioration
Understanding how it affects their symptoms could help doctors better tailor treatments to the individual needs of fibromyalgia patients