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NICE recommends Saxenda only for adults within specialist weight management services (Tier 3 or 4), with specific BMI thresholds and conditions

In addition to those taking the medications listed above, certain people should avoid berberine due to its risk for more serious health complications: Berberine is not safe to use during pregnancy or while breastfeeding

Your body needs several weeks to stabilize at each new level, which is why rushing escalation often backfires with side effects

2001 May;65(5):1104-11