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IGF-mediated proliferation process of theca cell has been verified in ex vivo model of sheep, to the extent that high IGF levels led to theca cell overgrowth [12]

The results for WR after surgery demonstrated similarly non-significant findings across all demographic variables

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10,11,15 Aging skin displays fragmentation of collagen and elastin fibers by the action of matrix metalloproteinase (MMPs), and increased mitochondrial oxidative stress results in deletions of mitochondrial DNA via the c-Jun/AP-1 pathway in dermal fibroblasts (Figure 1)