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Individualizing Treatment Goals While weight reduction is a hallmark of GLP-1 therapy, the ideal target varies: Older adults may need more conservative dosing to prevent frailty Patients with polypharmacy or advanced CKD require closer monitoring Ethnicity, comorbidities and baseline weight all influence treatment strategy Personalization remains essential for balancing efficacy and safety

Nestin, GAP43, -tubulin III, and Doublecortin mRNA levels increased by 1.7-, 1.6-, 1.8-, and 1.7-fold, respectively, in Epitalon-treated cells compared to untreated controls

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In the Mayo Clinic study, women and people who also reported having constipation on the GLP-1 medications were more likely to receive a diagnosis of gastroparesis

Effect of Heat Stress on Fatty Acids Profiles of Aloe Vera and Bryophyllum Pinnatum Leaves