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Tryptophan-related metabolites, including kynurenate, xanthurenate, and serotonin, were reduced 2- to 10-fold in PBH in the fasting state

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The structural diversity of these compounds is attributed to their biosynthetic origins, including organosulfur compounds from Allium species, glucosinolates from cruciferous vegetables, and other sulfur metabolites from microbial and marine sources

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Meanwhile, the weekly injection came in at 14.9% average reduction across a similar duration

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