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While GLP-1s are designed to target fat, studies suggest 15% and 40% of weight loss may come from muscle and other lean tissue without proper nutrition and strength training

J Biol Chem 1967

7 The intellectually responsible position, then, is this: cagrilintide almost certainly slows gastric emptying acutely, by the same vagal mechanism as native amylin and pramlintide, because it engages the same receptors in the same hindbrain region

Of the remaining 17 studies (which were evaluated for applicability by reading the full text), a further 10 were omitted per the exclusion criteria, leaving a total of 7 included studies (10-12,14-17)

When applying the DI-AIH definition, some of the cases fulfilled the criteria