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In another 2006 clinical trial, (10) 72 test subjects with pressure ulcers were presented with TB-500

These are associations rather than proof that altering NNMT activity reverses metabolic changes, but they motivate continued research into NNMT inhibitors in metabolic models

Other drugs found to inhibit vitamin B 12 absorption from food include cholestyramine (a bile acid-binding resin used in the treatment of high cholesterol), chloramphenicol and neomycin (antibiotics), and colchicine (medicine for gout treatment)

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